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單磷酰脂質(zhì)A(MPLA)可從細(xì)菌類脂A中提取或通過化學(xué)法合成。[1]

PHAD單磷酰脂質(zhì)A^™已用于：

• 作為鈷卟啉-磷脂(Co-PoP)脂質(zhì)體組分，用于使用gp41包膜蛋白的近膜端外部區(qū)(MPER)免疫小鼠[2]

• 與(DDA)共同作為佐劑，用于基于沙眼衣原體重組膜蛋白的多亞單位疫苗[3]

• 用作呼吸道合胞病毒(RSV)融合(F)蛋白FI-RSV疫苗的toll樣受體4(TLR4)激動(dòng)劑佐劑 [4]

2 mL 棕色玻璃鉗口蓋瓶 (699800P-1 mg)

2 mL 棕色玻璃鉗口蓋瓶 (699800P-5 mg)

Soluble in ethanol at 1mg/mL, soluble in DMSO at 5mg/mL, soluble in Chloroform:Methanol:Water at 5mg/mL, insoluble in water (aqueous buffers, serum etc.); however, it can be dispersed in an aqueous medium using a suitable emulsifier or detergent. This species is soluble in chloroform (at least up to 50 mg/mL) and chloroform:methanol solvent systems, however gentle heating and sonication may be necessary to aid in dissolution. Dropwise additions of methanol or water may aid dissolution in chloroform at higher concentrations. If using in combination with other lipids, dissolve this lipid separately and then combine dissolved lipids in their respective solvent solutions.

僅供研發(fā)使用。不用于藥物、家庭或其他用途。