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增殖細(xì)胞核抗原(內(nèi)參)單克隆抗體介紹

來(lái)源:青島捷世康生物科技有限公司   2025年07月17日 10:29  
產(chǎn)品編號(hào)bsm-33035M
英文名稱PCNA Mouse mAb, Nuclear Loading Control
中文名稱增殖細(xì)胞核抗原(內(nèi)參)單克隆抗體
別    名Cyclin; DNA polymerase delta auxiliary protein; HGCN8729; MGC8367; Mutagen-sensitive 209 protein; Pcna/cyclin; PCNAR; Polymerase delta accessory protein; Proliferating Cell Nuclear Antigen
產(chǎn)品類型內(nèi)參抗體
研究領(lǐng)域腫瘤  細(xì)胞生物  細(xì)胞周期蛋白  轉(zhuǎn)錄調(diào)節(jié)因子  細(xì)胞類型標(biāo)志物
抗體來(lái)源Mouse
克隆類型Monoclonal
克 隆 號(hào)10E9
交叉反應(yīng)Human,Mouse,Rat
產(chǎn)品應(yīng)用WB=1:500-5000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,Flow-Cyt=1:50
           not yet tested in other applications.
           optimal dilutions/concentrations should be determined by the end user.
理論分子量29 kDa
檢測(cè)分子量
細(xì)胞定位細(xì)胞核
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human PCNA
亞    型IgG
純化方法affinity purified by Protein G
緩 沖 液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng)This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMedPubMed
產(chǎn)品介紹Proliferating cell nuclear antigen (PCNA) is a 28kDa nuclear protein associated with the cell cycle, a nuclear protein vital for cellular DNA synthesis. Proliferating cell nuclear antigen was originally identified by immunofluorescence as a nuclear protein whose appearance correlated with the proliferate state of the cell. PCNA is required for replication of DNA in vitro and has been identified as the auxiliary protein (cofactor) for DNA polymerase delta. The anti-PCNA antibodies react with the nuclei of proliferating cells. PCNA is essential for cellular DNA synthesis and is also required for the in vitro replication of simian virus 40 (SV40) DNA where it acts to coordinate leading and lagging strand synthesis at the replication fork. The PCNA protein may fulfil several separate roles in the cell nucleus associated with changes in its antigenic structure.



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